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Chronic Hyperglycaemia Inhibits Tricarboxylic Acid Cycle in Rat Cardiomyoblasts Overexpressing Glucose Transporter Type 4

An oversupply of nutrients with a loss of metabolic flexibility and subsequent cardiac dysfunction are hallmarks of diabetic cardiomyopathy. Even if excess substrate is offered, the heart suffers energy depletion as metabolic fluxes are diminished. To study the effects of a high glucose supply, a st...

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Detalles Bibliográficos
Autores principales: Stratmann, Bernd, Eggers, Britta, Mattern, Yvonne, Silva de Carvalho, Tayana, Marcus, Katrin, Tschoepe, Diethelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266806/
https://www.ncbi.nlm.nih.gov/pubmed/35806260
http://dx.doi.org/10.3390/ijms23137255