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Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability

Thermal unfolding methods are commonly used as a predictive technique by tracking the protein’s physical properties. Inherent protein thermal stability and unfolding profiles of biotherapeutics can help to screen or study potential drugs and to find stabilizing or destabilizing conditions. Different...

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Detalles Bibliográficos
Autores principales: Kopra, Kari, Valtonen, Salla, Mahran, Randa, Kapp, Jonas N., Hassan, Nazia, Gillette, William, Dennis, Bryce, Li, Lianbo, Westover, Kenneth D., Plückthun, Andreas, Härmä, Harri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266822/
https://www.ncbi.nlm.nih.gov/pubmed/35806100
http://dx.doi.org/10.3390/ijms23137095