Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration

Kiteplatin, [PtCl(2)(cis-1,4-DACH)] (DACH = diaminocyclohexane), contains an isomeric form of the oxaliplatin diamine ligand trans-1R,2R-DACH and has been proposed as a valuable drug candidate against cisplatin- and oxaliplatin-resistant tumors, in particular, colorectal cancer. To further improve t...

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Detalles Bibliográficos
Autores principales: Barbanente, Alessandra, Gandin, Valentina, Ceresa, Cecilia, Marzano, Cristina, Ditaranto, Nicoletta, Hoeschele, James D., Natile, Giovanni, Arnesano, Fabio, Pacifico, Concetta, Intini, Francesco P., Margiotta, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266928/
https://www.ncbi.nlm.nih.gov/pubmed/35806087
http://dx.doi.org/10.3390/ijms23137081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266928/
https://www.ncbi.nlm.nih.gov/pubmed/35806087
http://dx.doi.org/10.3390/ijms23137081

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