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Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond †

Short peptides have great potential as safe and effective anticancer drug leads. Herein, the influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient-derived melanoma cells was investigated. Cyclic peptides such as cyclo(Leu-Ile-Ile-Leu-Val-Pro-Pro-Phe-Phe-), called CLA,...

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Detalles Bibliográficos
Autores principales: Bojarska, Joanna, Breza, Martin, Remko, Milan, Czyz, Malgorzata, Gajos-Michniewicz, Anna, Zimecki, Michał, Kaczmarek, Krzysztof, Madura, Izabela D., Wojciechowski, Jakub M., Wolf, Wojciech M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266943/
https://www.ncbi.nlm.nih.gov/pubmed/35806175
http://dx.doi.org/10.3390/ijms23137173