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Beneficial and Detrimental Roles of Heme Oxygenase-1 in the Neurovascular System
Heme oxygenase (HO) has both beneficial and detrimental effects via its metabolites, including carbon monoxide (CO), biliverdin or bilirubin, and ferrous iron. HO-1 is an inducible form of HO that is upregulated by oxidative stress, nitric oxide, CO, and hypoxia, whereas HO-2 is a constitutive form...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266949/ https://www.ncbi.nlm.nih.gov/pubmed/35806040 http://dx.doi.org/10.3390/ijms23137041 |