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A Novel Neurofilament Light Chain ELISA Validated in Patients with Alzheimer’s Disease, Frontotemporal Dementia, and Subjective Cognitive Decline, and the Evaluation of Candidate Proteins for Immunoassay Calibration

Neurofilament light chain (Nf-L) is a well-known biomarker for axonal damage; however, the corresponding circulating Nf-L analyte in cerebrospinal fluid (CSF) is poorly characterized. We therefore isolated new monoclonal antibodies against synthetic peptides, and these monoclonals were characterized...

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Detalles Bibliográficos
Autores principales: Das, Shreyasee, Dewit, Nele, Jacobs, Dirk, Pijnenburg, Yolande A. L., In ‘t Veld, Sjors G. J. G., Coppens, Salomé, Quaglia, Milena, Hirtz, Christophe, Teunissen, Charlotte E., Vanmechelen, Eugeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266977/
https://www.ncbi.nlm.nih.gov/pubmed/35806226
http://dx.doi.org/10.3390/ijms23137221