Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design

The human genome codes only a few thousand druggable proteins, mainly receptors and enzymes. While this pool of available drug targets is limited, there is an untapped potential for discovering new drug-binding mechanisms and modes. For example, enzymes with long binding cavities offer numerous prer...

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Detalles Bibliográficos
Autores principales: Bálint, Mónika, Zsidó, Balázs Zoltán, van der Spoel, David, Hetényi, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267029/
https://www.ncbi.nlm.nih.gov/pubmed/35806314
http://dx.doi.org/10.3390/ijms23137313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267029/
https://www.ncbi.nlm.nih.gov/pubmed/35806314
http://dx.doi.org/10.3390/ijms23137313

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