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Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design
The human genome codes only a few thousand druggable proteins, mainly receptors and enzymes. While this pool of available drug targets is limited, there is an untapped potential for discovering new drug-binding mechanisms and modes. For example, enzymes with long binding cavities offer numerous prer...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267029/ https://www.ncbi.nlm.nih.gov/pubmed/35806314 http://dx.doi.org/10.3390/ijms23137313 |