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Overexpression of UBA5 in Cells Mimics the Phenotype of Cells Lacking UBA5

Ufmylation is a posttranslational modification in which the modifier UFM1 is attached to target proteins. This conjugation requires the concerted work of three enzymes named UBA5, UFC1, and UFL1. Initially, UBA5 activates UFM1 in a process that ends with UFM1 attached to UBA5’s active site Cys. Then...

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Detalles Bibliográficos
Autores principales: Kumari, Sujata, Banerjee, Sayanika, Kumar, Manoj, Hayashi, Arata, Solaimuthu, Balakrishnan, Cohen-Kfir, Einav, Shaul, Yoav D., Rouvinski, Alexander, Wiener, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267032/
https://www.ncbi.nlm.nih.gov/pubmed/35806453
http://dx.doi.org/10.3390/ijms23137445