Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates

Excessive fetal growth is associated with DNA methylation alterations in human hematopoietic stem and progenitor cells (HSPC), but their functional impact remains elusive. We implemented an integrative analysis combining single-cell epigenomics, single-cell transcriptomics, and in vitro analyses to...

Descripción completa

Detalles Bibliográficos
Autores principales: Pelletier, Alexandre, Carrier, Arnaud, Zhao, Yongmei, Canouil, Mickaël, Derhourhi, Mehdi, Durand, Emmanuelle, Berberian-Ferrato, Lionel, Greally, John, Hughes, Francine, Froguel, Philippe, Bonnefond, Amélie, Delahaye, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267056/
https://www.ncbi.nlm.nih.gov/pubmed/35806330
http://dx.doi.org/10.3390/ijms23137323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267056/
https://www.ncbi.nlm.nih.gov/pubmed/35806330
http://dx.doi.org/10.3390/ijms23137323

Ejemplares similares