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Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates
Excessive fetal growth is associated with DNA methylation alterations in human hematopoietic stem and progenitor cells (HSPC), but their functional impact remains elusive. We implemented an integrative analysis combining single-cell epigenomics, single-cell transcriptomics, and in vitro analyses to...
Autores principales: | Pelletier, Alexandre, Carrier, Arnaud, Zhao, Yongmei, Canouil, Mickaël, Derhourhi, Mehdi, Durand, Emmanuelle, Berberian-Ferrato, Lionel, Greally, John, Hughes, Francine, Froguel, Philippe, Bonnefond, Amélie, Delahaye, Fabien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267056/ https://www.ncbi.nlm.nih.gov/pubmed/35806330 http://dx.doi.org/10.3390/ijms23137323 |
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