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Linking Late Endosomal Cholesterol with Cancer Progression and Anticancer Drug Resistance

Cancer cells undergo drastic metabolic adaptions to cover increased bioenergetic needs, contributing to resistance to therapies. This includes a higher demand for cholesterol, which often coincides with elevated cholesterol uptake from low-density lipoproteins (LDL) and overexpression of the LDL rec...

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Detalles Bibliográficos
Autores principales: Nguyen, Mai K. L., Jose, Jaimy, Wahba, Mohamed, Bernaus-Esqué, Marc, Hoy, Andrew J., Enrich, Carlos, Rentero, Carles, Grewal, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267071/
https://www.ncbi.nlm.nih.gov/pubmed/35806209
http://dx.doi.org/10.3390/ijms23137206