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The Transcription Coregulator RIP140 Inhibits Cancer Cell Proliferation by Targeting the Pentose Phosphate Pathway

Cancer cells switch their metabolism toward glucose metabolism to sustain their uncontrolled proliferation. Consequently, glycolytic intermediates are diverted into the pentose phosphate pathway (PPP) to produce macromolecules necessary for cell growth. The transcription regulator RIP140 controls gl...

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Detalles Bibliográficos
Autores principales: Jacquier, Valentin, Gitenay, Delphine, Cavaillès, Vincent, Teyssier, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267222/
https://www.ncbi.nlm.nih.gov/pubmed/35806424
http://dx.doi.org/10.3390/ijms23137419