Complete Reaction Phenotyping of Propranolol and 4-Hydroxypropranolol with the 19 Enzymes of the Human UGT1 and UGT2 Families

Propranolol is a competitive non-selective beta-receptor antagonist that is available on the market as a racemic mixture. In the present study, glucuronidation of propranolol and its equipotent phase I metabolite 4-hydroxypropranolol by all 19 members of the human UGT1 and UGT2 families was monitore...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Fan, Liu, Sijie, Wolber, Gerhard, Bureik, Matthias, Parr, Maria Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267274/
https://www.ncbi.nlm.nih.gov/pubmed/35806479
http://dx.doi.org/10.3390/ijms23137476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267274/
https://www.ncbi.nlm.nih.gov/pubmed/35806479
http://dx.doi.org/10.3390/ijms23137476

Ejemplares similares