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SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development

Ubiquitin (ub) is a small, highly conserved protein widely expressed in eukaryotic cells. Ubiquitination is a post-translational modification catalyzed by enzymes that activate, conjugate, and ligate ub to proteins. Substrates can be modified either by addition of a single ubiquitin molecule (monoub...

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Detalles Bibliográficos
Autores principales: El-Saafin, Farrah, Devys, Didier, Johnsen, Steven A., Vincent, Stéphane D., Tora, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267394/
https://www.ncbi.nlm.nih.gov/pubmed/35806465
http://dx.doi.org/10.3390/ijms23137459