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Limited Accuracy of Pan-Trk Immunohistochemistry Screening for NTRK Rearrangements in Follicular-Derived Thyroid Carcinoma

Patients with advanced thyroid cancer harboring NTRK rearrangements can be treated with highly effective selective inhibitors. Immunohistochemistry (IHC) analysis, to detect Trk protein expression, represents an appealing screening strategy for NTRK rearrangements, but its efficacy has been poorly e...

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Detalles Bibliográficos
Autores principales: Macerola, Elisabetta, Proietti, Agnese, Poma, Anello Marcello, Vignali, Paola, Sparavelli, Rebecca, Ginori, Alessandro, Basolo, Alessio, Elisei, Rossella, Santini, Ferruccio, Basolo, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9267555/
https://www.ncbi.nlm.nih.gov/pubmed/35806472
http://dx.doi.org/10.3390/ijms23137470