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Cholesterol Alters the Phase Separation in Model Membranes Containing hBest1

Human retinal pigment epithelial (RPE) cells express the transmembrane Ca(2+)-dependent Cl(−) channel bestrophin-1 (hBest1) of the plasma membrane. Mutations in the hBest1 protein are associated with the development of distinct pathological conditions known as bestrophinopathies. The interactions be...

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Detalles Bibliográficos
Autores principales: Videv, Pavel, Mladenova, Kirilka, Andreeva, Tonya D., Park, Jong Hun, Moskova-Doumanova, Veselina, Petrova, Svetla D., Doumanov, Jordan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268032/
https://www.ncbi.nlm.nih.gov/pubmed/35807512
http://dx.doi.org/10.3390/molecules27134267