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In Vivo Evaluation of (−)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site

Microtubule-stabilizing agents (MSAs) are a class of compounds used in the treatment of triple-negative breast cancer (TNBC), a subtype of breast cancer where chemotherapy remains the standard-of-care for patients. Taxanes like paclitaxel and docetaxel have demonstrated efficacy against TNBC in the...

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Detalles Bibliográficos
Autores principales: Takahashi-Ruiz, Leila, Morris, Joseph D., Crews, Phillip, Johnson, Tyler A., Risinger, April L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268097/
https://www.ncbi.nlm.nih.gov/pubmed/35807495
http://dx.doi.org/10.3390/molecules27134244