Cargando…
In Vivo Evaluation of (−)-Zampanolide Demonstrates Potent and Persistent Antitumor Efficacy When Targeted to the Tumor Site
Microtubule-stabilizing agents (MSAs) are a class of compounds used in the treatment of triple-negative breast cancer (TNBC), a subtype of breast cancer where chemotherapy remains the standard-of-care for patients. Taxanes like paclitaxel and docetaxel have demonstrated efficacy against TNBC in the...
Autores principales: | Takahashi-Ruiz, Leila, Morris, Joseph D., Crews, Phillip, Johnson, Tyler A., Risinger, April L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268097/ https://www.ncbi.nlm.nih.gov/pubmed/35807495 http://dx.doi.org/10.3390/molecules27134244 |
Ejemplares similares
-
New Zampanolide Mimics: Design, Synthesis, and Antiproliferative Evaluation
por: Chen, Guanglin, et al.
Publicado: (2020) -
Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads
por: Chen, Qiao-Hong, et al.
Publicado: (2014) -
Microtubule-Stabilizing Drugs from Marine Sponges: Focus on Peloruside A and Zampanolide
por: Miller, John H., et al.
Publicado: (2010) -
429 Eribulin Synergizes with STING Agonists by Enhancing Type 1 Interferon Expression and Improves Antitumor Efficacy as Combination Treatment
por: Takahashi-Ruiz, Leila, et al.
Publicado: (2023) -
Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration
por: Field, Jessica J., et al.
Publicado: (2017)