Regioselective One-Pot Synthesis, Biological Activity and Molecular Docking Studies of Novel Conjugates N-(p-Aryltriazolyl)-1,5-benzodiazepin-2-ones as Potent Antibacterial and Antifungal Agents

Novel 1,2,3-triazolo-linked-1,5-benzodiazepinones were designed and synthesized via a Cu(I)-catalyzed 1,3-dipolar alkyne-azide coupling reaction (CuAAC). The chemical structures of these compounds were confirmed by (1)H NMR, (13)C NMR, HMBC, HRMS, and elemental analysis. The compounds were screened...

Descripción completa

Detalles Bibliográficos
Autores principales: Nsira, Asma, Mtiraoui, Hasan, Chniti, Sami, Al-Ghulikah, Hanan, Gharbi, Rafik, Msaddek, Moncef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268147/
https://www.ncbi.nlm.nih.gov/pubmed/35807263
http://dx.doi.org/10.3390/molecules27134015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268147/
https://www.ncbi.nlm.nih.gov/pubmed/35807263
http://dx.doi.org/10.3390/molecules27134015

Ejemplares similares