Cargando…

Regioselective One-Pot Synthesis, Biological Activity and Molecular Docking Studies of Novel Conjugates N-(p-Aryltriazolyl)-1,5-benzodiazepin-2-ones as Potent Antibacterial and Antifungal Agents

Novel 1,2,3-triazolo-linked-1,5-benzodiazepinones were designed and synthesized via a Cu(I)-catalyzed 1,3-dipolar alkyne-azide coupling reaction (CuAAC). The chemical structures of these compounds were confirmed by (1)H NMR, (13)C NMR, HMBC, HRMS, and elemental analysis. The compounds were screened...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nsira, Asma, Mtiraoui, Hasan, Chniti, Sami, Al-Ghulikah, Hanan, Gharbi, Rafik, Msaddek, Moncef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268147/ https://www.ncbi.nlm.nih.gov/pubmed/35807263 http://dx.doi.org/10.3390/molecules27134015

Ejemplares similares

Silica: An efficient catalyst for one-pot regioselective synthesis of dithioethers
por: Kundu, Samir, et al.
Publicado: (2014)

Regioselective Allene Hydroarylation via One-Pot Allene Hydrosilylation/Pd-Catalyzed Cross-Coupling
por: Miller, Zachary D., et al.
Publicado: (2014)

Substrate controlled, regioselective carbopalladation for the one-pot synthesis of C4-substituted tetrahydroisoquinoline analogues
por: Krishna Reddy, Singarajanahalli Mundarinti, et al.
Publicado: (2020)

Orthogonal protection of saccharide polyols through solvent-free one-pot sequences based on regioselective silylations
por: Traboni, Serena, et al.
Publicado: (2016)

Regioselective, one-pot, multi-component, green synthesis of substituted benzo[c]pyrazolo[2,7]naphthyridines
por: Ashraf, Abida, et al.
Publicado: (2020)

Pot economy and one-pot synthesis
por: Hayashi, Yujiro
Publicado: (2016)

Catalytic asymmetric synthesis of N-substituted tetrahydroquinoxalines via regioselective Heyns rearrangement and stereoselective transfer hydrogenation in one pot
por: Huang, Jin, et al.
Publicado: (2021)

Regioselective Ru(II)/Pd(0) Dual Catalysis: One-Pot C–H Diarylation of Five-Membered Heterocyclic Derivatives
por: Al Mamari, Hamad H., et al.
Publicado: (2021)

One-pot regioselective C–H activation iodination–cyanation of 2,4-diarylquinazolines using malononitrile as a cyano source
por: Yan, Ziqiao, et al.
Publicado: (2019)

One-Pot FDCA Diester Synthesis from Mucic Acid and Their Solvent-Free Regioselective Polytransesterification for Production of Glycerol-Based Furanic Polyesters
por: Zhao, Deyang, et al.
Publicado: (2019)

One-pot synthesis of (−)-Ambrox
por: Yang, Shaoxiang, et al.
Publicado: (2016)

Bismuth (III) Salts Promoted and Ionic Liquid Assisted an Efficient and Environmentally Benign One-Pot Synthesis of 1,5-Benzodiazepine Derivatives
por: Chaskar, Atul, et al.
Publicado: (2011)

Ferrocene anchored activated carbon as a versatile catalyst for the synthesis of 1,5-benzodiazepines via one-pot environmentally benign conditions
por: Kusuma, Suman, et al.
Publicado: (2022)

Regioselective One-Pot Synthesis of Hydroxy-(S)-Equols Using Isoflavonoid Reductases and Monooxygenases and Evaluation of the Hydroxyequol Derivatives as Selective Estrogen Receptor Modulators and Antioxidants
por: Song, Hanbit, et al.
Publicado: (2022)

One-Pot Silver Nanoring Synthesis
por: Drogat, Nicolas, et al.
Publicado: (2009)

One-pot aminobenzylation of aldehydes with toluenes
por: Wang, Zhiting, et al.
Publicado: (2018)

Stereoselective one-pot synthesis of polypropionates
por: Ho, Guo-Ming, et al.
Publicado: (2017)

Efficient One-Pot Synthesis of Indolhydroxy Derivatives Catalyzed by SnCl(2), DFT Calculations and Docking Study
por: Hakmaoui, Yassine, et al.
Publicado: (2022)

Catalyst-free synthesis of novel 1,5-benzodiazepines and 3,4-dihydroquinoxalines using isocyanide-based one-pot, three- and four-component reactions
por: Mohlala, Reagan L., et al.
Publicado: (2021)

Crystal structure of 2-isopropyl-5,7′-dimethyl-1′,3′,3a’,6′,8a’,8b’-hexahydrospiro[cyclohexane-1,6′-furo[3,4-d]imidazo[1,5-b]isoxazol]-8′(7′H)-one
por: Abda, Heithem, et al.
Publicado: (2016)

One-Step Regioselective Synthesis of Benzofurans from Phenols and α-Haloketones
por: Wang, Bingqiao, et al.
Publicado: (2019)

One-Pot Synthesis of Polypyrazoles by Click Reactions
por: Wang, Shasha, et al.
Publicado: (2017)

One-Pot Enzymatic Production of Lignin-Composites
por: Ion, Sabina, et al.
Publicado: (2018)

Hierarchical and programmable one-pot synthesis of oligosaccharides
por: Cheng, Cheng-Wei, et al.
Publicado: (2018)

Oxidation-Induced “One-Pot” Click Chemistry
por: Albada, Bauke, et al.
Publicado: (2021)

A novel one-pot synthesis of flavones
por: Chang, Meng-Yang, et al.
Publicado: (2021)

Trimethylaluminum-mediated one-pot peptide elongation
por: Hattori, Tomohiro, et al.
Publicado: (2023)

Recent Progress on One-Pot Multisubstrate Screening
por: Fogel, Matisyahu S., et al.
Publicado: (2023)

One-Pot, One-Step Synthesis of Drug-Loaded Magnetic Multimicelle Aggregates
por: Kim, Chang Soo, et al.
Publicado: (2022)

Immobilized nickel boride nanoparticles on magnetic functionalized multi-walled carbon nanotubes: a new nanocomposite for the efficient one-pot synthesis of 1,4-benzodiazepines
por: Mohammad Aminzadeh, Farkhondeh, et al.
Publicado: (2023)

Crystal structure of (1S,2S,2′R,3a′S,5R)-2′-[(5-bromo-1H-indol-3-yl)methyl]-2-isopropyl-5,5′-dimethyldihydro-2′H-spiro[cyclohexane-1,6′-imidazo[1,5-b]isoxazol]-4′(5′H)-one
por: Ghannay, Siwar, et al.
Publicado: (2016)

Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity
por: Chaves-Carballo, Katherine, et al.
Publicado: (2022)

A One Pot, One Step, Precision Cloning Method with High Throughput Capability
por: Engler, Carola, et al.
Publicado: (2008)

One-Pot, Mix-and-Read Peptide-MHC Tetramers
por: Leisner, Christian, et al.
Publicado: (2008)

Isothiourea-Mediated One-Pot Synthesis of Functionalized Pyridines**
por: Stark, Daniel G, et al.
Publicado: (2013)

One-Pot, Three-Component Arylalkynyl Sulfone Synthesis
por: Chen, C. Chun, et al.
Publicado: (2015)

One-pot multistep mechanochemical synthesis of fluorinated pyrazolones
por: Howard, Joseph L, et al.
Publicado: (2017)

One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues
por: Zhao, Jianxiong, et al.
Publicado: (2018)

“Chocolate” Gold Nanoparticles—One Pot Synthesis and Biocompatibility
por: Roy Chowdhury, Neelika, et al.
Publicado: (2018)

One-Pot Chemoenzymatic Multicomponent Synthesis of Thiazole Derivatives
por: Zheng, Hui, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_dcqgksogl4nsu817i848p6u46m