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Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches

Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work, reversed-phase high-performance liquid chromatography and biomimetic chromatography were applied to characterize the lipophilicity of sulfonamide d...

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Detalles Bibliográficos
Autores principales: Pastewska, Monika, Żołnowska, Beata, Kovačević, Strahinja, Kapica, Hanna, Gromelski, Maciej, Stoliński, Filip, Sławiński, Jarosław, Sawicki, Wiesław, Ciura, Krzesimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268166/
https://www.ncbi.nlm.nih.gov/pubmed/35807212
http://dx.doi.org/10.3390/molecules27133965