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Molecular Analysis and Conformational Dynamics of Human MC4R Disease-Causing Mutations

Obesity is a chronic disease with increasing cases among children and adolescents. Melanocortin 4 receptor (MC4R) is a G protein-coupled transporter involved in solute transport, enabling it to maintain cellular homeostasis. MC4R mutations are associated with early-onset severe obesity, and the iden...

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Detalles Bibliográficos
Autores principales: Fatima, Munazza Tamkeen, Islam, Zeyaul, Kolatkar, Prasanna R., Al-Shabeeb Akil, Ammira Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268210/
https://www.ncbi.nlm.nih.gov/pubmed/35807283
http://dx.doi.org/10.3390/molecules27134037