Dimethyl Itaconate Reduces α-MSH-Induced Pigmentation via Modulation of AKT and p38 MAPK Signaling Pathways in B16F10 Mouse Melanoma Cells

Dimethyl itaconate (DMI) exhibits an anti-inflammatory effect. Activation of nuclear factor erythroid 2-related factor 2 (NRF2) is implicated in the inhibition of melanogenesis. Therefore, DMI and itaconic acid (ITA), classified as NRF2 activators, have potential uses in hyperpigmentation reduction....

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Detalles Bibliográficos
Autores principales: Jang, Sungchan, Chi, Won-Jae, Kim, Seung-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268225/
https://www.ncbi.nlm.nih.gov/pubmed/35807430
http://dx.doi.org/10.3390/molecules27134183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268225/
https://www.ncbi.nlm.nih.gov/pubmed/35807430
http://dx.doi.org/10.3390/molecules27134183

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