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Drug D, a Diosgenin Derive, Inhibits L-Arginine-Induced Acute Pancreatitis through Meditating GSDMD in the Endoplasmic Reticulum via the TXNIP/HIF-1α Pathway

Acute pancreatitis (AP) is one of the most common causes of hospitalization for gastrointestinal diseases, with high morbidity and mortality. Endoplasmic reticulum stress (ERS) and Gasdermin D (GSDMD) mediate AP, but little is known about their mutual influence on AP. Diosgenin has excellent anti-in...

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Detalles Bibliográficos
Autores principales: Zhang, Cuicui, Niu, Hai, Wan, Chengyu, Yu, Xiuxian, Xin, Guang, Zhu, Yuda, Wei, Zeliang, Li, Fan, Wang, Yilan, Zhang, Kun, Li, Shiyi, Dong, Yuman, Li, Yangying, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268286/
https://www.ncbi.nlm.nih.gov/pubmed/35807771
http://dx.doi.org/10.3390/nu14132591