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Domino Nitro Reduction-Friedländer Heterocyclization for the Preparation of Quinolines

The Friedländer synthesis offers efficient access to substituted quinolines from 2-aminobenzaldehydes and activated ketones in the presence of a base. The disadvantage of this procedure lies in the fact that relatively few 2-aminobenzaldehyde derivatives are readily available. To overcome this probl...

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Detalles Bibliográficos
Autores principales: Fobi, Kwabena, Bunce, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268355/
https://www.ncbi.nlm.nih.gov/pubmed/35807369
http://dx.doi.org/10.3390/molecules27134123