Broad betacoronavirus neutralization by a stem helix–specific human antibody

The spillovers of betacoronaviruses in humans and the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad coronavirus countermeasures. We describe five monoclonal antibodies (mAbs) cross-reacting with the stem helix of multiple betacoronavi...

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Detalles Bibliográficos
Autores principales: Pinto, Dora, Sauer, Maximilian M., Czudnochowski, Nadine, Low, Jun Siong, Tortorici, M. Alejandra, Housley, Michael P., Noack, Julia, Walls, Alexandra C., Bowen, John E., Guarino, Barbara, Rosen, Laura E., di Iulio, Julia, Jerak, Josipa, Kaiser, Hannah, Islam, Saiful, Jaconi, Stefano, Sprugasci, Nicole, Culap, Katja, Abdelnabi, Rana, Foo, Caroline, Coelmont, Lotte, Bartha, Istvan, Bianchi, Siro, Silacci-Fregni, Chiara, Bassi, Jessica, Marzi, Roberta, Vetti, Eneida, Cassotta, Antonino, Ceschi, Alessandro, Ferrari, Paolo, Cippà, Pietro E., Giannini, Olivier, Ceruti, Samuele, Garzoni, Christian, Riva, Agostino, Benigni, Fabio, Cameroni, Elisabetta, Piccoli, Luca, Pizzuto, Matteo S., Smithey, Megan, Hong, David, Telenti, Amalio, Lempp, Florian A., Neyts, Johan, Havenar-Daughton, Colin, Lanzavecchia, Antonio, Sallusto, Federica, Snell, Gyorgy, Virgin, Herbert W., Beltramello, Martina, Corti, Davide, Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268357/
https://www.ncbi.nlm.nih.gov/pubmed/34344823
http://dx.doi.org/10.1126/science.abj3321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268357/
https://www.ncbi.nlm.nih.gov/pubmed/34344823
http://dx.doi.org/10.1126/science.abj3321

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