Steroidal Antimetabolites Protect Mice against Trypanosoma brucei

Trypanosoma brucei, the causative agent for human African trypanosomiasis, is an emerging ergosterol-dependent parasite that produces chokepoint enzymes, sterol methyltransferases (SMT), not synthesized in their animal hosts that can regulate cell viability. Here, we report the lethal effects of two...

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Detalles Bibliográficos
Autores principales: Chaudhuri, Minu, Singha, Ujjal K., Vanderloop, Boden H., Tripathi, Anuj, Nes, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268410/
https://www.ncbi.nlm.nih.gov/pubmed/35807334
http://dx.doi.org/10.3390/molecules27134088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268410/
https://www.ncbi.nlm.nih.gov/pubmed/35807334
http://dx.doi.org/10.3390/molecules27134088

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