Quantitative Determination of Four Potential Genotoxic Impurities in the Active Pharmaceutical Ingredients in TSD-1 Using UPLC-MS/MS

A novel method of ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was developed for the identification and quantification of four potential genotoxic impurities (PGIs) in the active pharmaceutical ingredients of TSD-1, a novel P2Y(12) receptor antagonist. Four PGIs were...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Taiyu, Yang, Hailong, Yang, Jie, Guo, Ningjie, Wu, Guodong, Xu, Xueyu, An, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268482/
https://www.ncbi.nlm.nih.gov/pubmed/35807373
http://dx.doi.org/10.3390/molecules27134129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268482/
https://www.ncbi.nlm.nih.gov/pubmed/35807373
http://dx.doi.org/10.3390/molecules27134129

Ejemplares similares