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The Natural Janus Kinase Inhibitor Agerarin Downregulates Interleukin-4-Induced PER2 Expression in HaCaT Keratinocytes

The circadian clock system is closely associated with inflammatory responses. Dysregulation of the circadian clock genes in the skin impairs the skin barrier function and affects the pathophysiology of atopic dermatitis. Interleukin 4 (IL-4) is a proinflammatory cytokine derived from T-helper type 2...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Yeon, Jung, Euitaek, Yeo, Hyunjin, Ahn, Sung Shin, Lim, Yoongho, Lee, Young Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268509/
https://www.ncbi.nlm.nih.gov/pubmed/35807451
http://dx.doi.org/10.3390/molecules27134205