Deep Learning and Structure-Based Virtual Screening for Drug Discovery against NEK7: A Novel Target for the Treatment of Cancer

NIMA-related kinase7 (NEK7) plays a multifunctional role in cell division and NLRP3 inflammasone activation. A typical expression or any mutation in the genetic makeup of NEK7 leads to the development of cancer malignancies and fatal inflammatory disease, i.e., breast cancer, non-small cell lung can...

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Detalles Bibliográficos
Autores principales: Aziz, Mubashir, Ejaz, Syeda Abida, Zargar, Seema, Akhtar, Naveed, Aborode, Abdullahi Tunde, A. Wani, Tanveer, Batiha, Gaber El-Saber, Siddique, Farhan, Alqarni, Mohammed, Akintola, Ashraf Akintayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268522/
https://www.ncbi.nlm.nih.gov/pubmed/35807344
http://dx.doi.org/10.3390/molecules27134098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268522/
https://www.ncbi.nlm.nih.gov/pubmed/35807344
http://dx.doi.org/10.3390/molecules27134098

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