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Deep Learning and Structure-Based Virtual Screening for Drug Discovery against NEK7: A Novel Target for the Treatment of Cancer
NIMA-related kinase7 (NEK7) plays a multifunctional role in cell division and NLRP3 inflammasone activation. A typical expression or any mutation in the genetic makeup of NEK7 leads to the development of cancer malignancies and fatal inflammatory disease, i.e., breast cancer, non-small cell lung can...
Autores principales: | Aziz, Mubashir, Ejaz, Syeda Abida, Zargar, Seema, Akhtar, Naveed, Aborode, Abdullahi Tunde, A. Wani, Tanveer, Batiha, Gaber El-Saber, Siddique, Farhan, Alqarni, Mohammed, Akintola, Ashraf Akintayo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268522/ https://www.ncbi.nlm.nih.gov/pubmed/35807344 http://dx.doi.org/10.3390/molecules27134098 |
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