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Controlled Delivery of an Anti-Inflammatory Toxin to Macrophages by Mutagenesis and Nanoparticle Modification

Advances in drug delivery systems (DDSs) have enabled the specific delivery of drugs to target cells. Subtilase cytotoxin (SubAB) produced by certain enterohemorrhagic Escherichia coli strains induces endoplasmic reticulum (ER) stress and suppresses nitric oxide generation in macrophages. We previou...

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Detalles Bibliográficos
Autores principales: Harada, Ayaka, Tsutsuki, Hiroyasu, Zhang, Tianli, Yahiro, Kinnosuke, Sawa, Tomohiro, Niidome, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268525/
https://www.ncbi.nlm.nih.gov/pubmed/35807998
http://dx.doi.org/10.3390/nano12132161