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Production and Quality Control of [(177)Lu]Lu-PSMA-I&T: Development of an Investigational Medicinal Product Dossier for Clinical Trials

Since prostate cancer is the most commonly diagnosed malignancy in men, the theranostic approach has become very attractive since the discovery of urea-based PSMA inhibitors. Different molecules have been synthesized starting from the Glu-urea-Lys scaffold as the pharmacophore and then optimizing th...

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Detalles Bibliográficos
Autores principales: Di Iorio, Valentina, Boschi, Stefano, Cuni, Cristina, Monti, Manuela, Severi, Stefano, Paganelli, Giovanni, Masini, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268543/
https://www.ncbi.nlm.nih.gov/pubmed/35807385
http://dx.doi.org/10.3390/molecules27134143