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Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic Acids through In Vitro, In Silico and In Vivo Studies

In the current study, a series of new (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has been synthesized. Initially, the aldehydic derivatives were isolated in the diastereomeric form, and the structures were confi...

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Detalles Bibliográficos
Autores principales: Mahmood, Fawad, Khan, Jamshaid Ali, Mahnashi, Mater H., Jan, Muhammad Saeed, Javed, Muhammad Aamir, Rashid, Umer, Sadiq, Abdul, Hassan, Syed Shams ul, Bungau, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268591/
https://www.ncbi.nlm.nih.gov/pubmed/35807316
http://dx.doi.org/10.3390/molecules27134068