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Enterohepatic Takeda G-Protein Coupled Receptor 5 Agonism in Metabolic Dysfunction-Associated Fatty Liver Disease and Related Glucose Dysmetabolism

Metabolic dysfunction-associated fatty liver disease (MAFLD) is a major health concern with no approved pharmacological therapies. Molecules developed to activate the bile acid-receptor TGR5 regulate pathways involved in MALFD pathogenesis, but the therapeutic value of TGR5 activation on the active...

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Detalles Bibliográficos
Autores principales: Gillard, Justine, Picalausa, Corinne, Ullmer, Christoph, Adorini, Luciano, Staels, Bart, Tailleux, Anne, Leclercq, Isabelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268629/
https://www.ncbi.nlm.nih.gov/pubmed/35807885
http://dx.doi.org/10.3390/nu14132707