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Disentangling Unusual Catalytic Properties and the Role of the [4Fe-4S] Cluster of Three Endonuclease III from the Extremophile D. radiodurans

Endonuclease III (EndoIII) is a bifunctional DNA glycosylase with specificity for a broad range of oxidized DNA lesions. The genome of an extremely radiation- and desiccation-resistant bacterium, Deinococcus radiodurans, possesses three genes encoding for EndoIII-like enzymes (DrEndoIII1, DrEndoIII2...

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Detalles Bibliográficos
Autores principales: Rollo, Filipe, Borges, Patricia T., Silveira, Célia M., Rosa, Margarida T. G., Todorovic, Smilja, Moe, Elin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268735/
https://www.ncbi.nlm.nih.gov/pubmed/35807515
http://dx.doi.org/10.3390/molecules27134270