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Approaches to Improve Macromolecule and Nanoparticle Accumulation in the Tumor Microenvironment by the Enhanced Permeability and Retention Effect

Passive targeting is the foremost mechanism by which nanocarriers and drug-bearing macromolecules deliver their payload selectively to solid tumors. An important driver of passive targeting is the enhanced permeability and retention (EPR) effect, which is the cornerstone of most carrier-based tumor-...

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Detalles Bibliográficos
Autores principales: Ejigah, Victor, Owoseni, Oluwanifemi, Bataille-Backer, Perpetue, Ogundipe, Omotola D., Fisusi, Funmilola A., Adesina, Simeon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268820/
https://www.ncbi.nlm.nih.gov/pubmed/35808648
http://dx.doi.org/10.3390/polym14132601