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Response of plasma microRNAs to nusinersen treatment in patients with SMA

OBJECTIVE: Spinal muscular atrophy (SMA) is a common genetic cause of infant mortality. Nusinersen treatment ameliorates the clinical outcome of SMA, however, some patients respond well, while others have limited response. We investigated microRNAs in blood samples from SMA patients and their respon...

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Detalles Bibliográficos
Autores principales: Zaharieva, Irina T., Scoto, Mariacristina, Aragon‐Gawinska, Karolina, Ridout, Deborah, Doreste, Bruno, Servais, Laurent, Muntoni, Francesco, Zhou, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268869/
https://www.ncbi.nlm.nih.gov/pubmed/35584175
http://dx.doi.org/10.1002/acn3.51579