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Remyelination in humans due to a retinoid‐X receptor agonist is age‐dependent

Remyelination efficiency declines with advancing age in animal models, but this has been harder to demonstrate in people with multiple sclerosis. We show that bexarotene, a putatively remyelinating retinoid‐X receptor agonist, shortened the visual evoked potential latency in patients with chronic op...

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Detalles Bibliográficos
Autores principales: McMurran, Christopher E., Mukherjee, Trisha, Brown, J William L., Michell, Andrew W., Chard, Declan T., Franklin, Robin J. M., Coles, Alasdair J., Cunniffe, Nick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9268872/
https://www.ncbi.nlm.nih.gov/pubmed/35587315
http://dx.doi.org/10.1002/acn3.51595