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Development and Characterization of Oral Raft Forming In Situ Gelling System of Neratinib Anticancer Drug Using 3(2) Factorial Design
Neratinib (NTB) is an irreversible inhibitor of pan-human epidermal growth factor receptor (HER-2) tyrosine kinase and is used in the treatment of breast cancer. It is a poorly aqueous soluble drug and exhibits extremely low oral bioavailability at higher pH, leading to a diminishing of the therapeu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269124/ https://www.ncbi.nlm.nih.gov/pubmed/35808569 http://dx.doi.org/10.3390/polym14132520 |