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Development and Characterization of Oral Raft Forming In Situ Gelling System of Neratinib Anticancer Drug Using 3(2) Factorial Design

Neratinib (NTB) is an irreversible inhibitor of pan-human epidermal growth factor receptor (HER-2) tyrosine kinase and is used in the treatment of breast cancer. It is a poorly aqueous soluble drug and exhibits extremely low oral bioavailability at higher pH, leading to a diminishing of the therapeu...

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Detalles Bibliográficos
Autores principales: Hani, Umme, Rahamathulla, Mohamed, Osmani, Riyaz Ali M., Begum, M.Yasmin, Wahab, Shadma, Ghazwani, Mohammed, Fatease, Adel Al, Alamri, Ali H., Gowda, Devegowda V., Alqahtani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269124/
https://www.ncbi.nlm.nih.gov/pubmed/35808569
http://dx.doi.org/10.3390/polym14132520