P2X(7) receptor-nitric oxide interaction mediates apoptosis in mouse immortalized mesangial cells exposed to high glucose

INTRODUCTION: Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia that leads to diabetic nephropathy (DN). We showed that P2X(7), a purinergic receptor, was highly expressed in DM; however, when oxidative stress was controlled, renal NO recovered, and the activation of this re...

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Detalles Bibliográficos
Autores principales: Fernandes, Thamires de Oliveira, Rodrigues, Adelson Marçal, Punaro, Giovana Rita, de Lima, Deyse Yorgos, Higa, Elisa Mieko Suemitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269184/
https://www.ncbi.nlm.nih.gov/pubmed/34694316
http://dx.doi.org/10.1590/2175-8239-JBN-2021-0086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269184/
https://www.ncbi.nlm.nih.gov/pubmed/34694316
http://dx.doi.org/10.1590/2175-8239-JBN-2021-0086

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