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Midazolam impacts acetyl—And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?

Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its proper metabolism, which can be triggered by ep...

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Detalles Bibliográficos
Autores principales: Rump, Katharina, Holtkamp, Caroline, Bergmann, Lars, Nowak, Hartmuth, Unterberg, Matthias, Orlowski, Jennifer, Thon, Patrick, Bazzi, Zainab, Bazzi, Maha, Adamzik, Michael, Koos, Björn, Rahmel, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269431/
https://www.ncbi.nlm.nih.gov/pubmed/35802656
http://dx.doi.org/10.1371/journal.pone.0271119