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Reduced CREB3L1 expression in triple negative and luminal a breast cancer cells contributes to enhanced cell migration, anchorage-independent growth and metastasis

Women with metastatic breast cancer have a disheartening 5-year survival rate of only 28%. CREB3L1 (cAMP-responsive element binding protein 3 like 1) is a metastasis suppressor that functions as a transcription factor, and in an estrogen-dependent model of rat breast cancer, it repressed the express...

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Detalles Bibliográficos
Autores principales: Mellor, Paul, Kendall, Stephanie, Smith, Shari, Saxena, Anurag, Anderson, Deborah H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269740/
https://www.ncbi.nlm.nih.gov/pubmed/35802566
http://dx.doi.org/10.1371/journal.pone.0271090