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Enzymatic incorporation of an isotope-labeled adenine into RNA for the study of conformational dynamics by NMR

Solution NMR spectroscopy is a well-established tool with unique advantages for structural studies of RNA molecules. However, for large RNA sequences, the NMR resonances often overlap severely. A reliable way to perform resonance assignment and allow further analysis despite spectral crowding is the...

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Detalles Bibliográficos
Autores principales: Feyrer, Hannes, Gurdap, Cenk Onur, Marušič, Maja, Schlagnitweit, Judith, Petzold, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269771/
https://www.ncbi.nlm.nih.gov/pubmed/35802676
http://dx.doi.org/10.1371/journal.pone.0264662