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Enzymatic incorporation of an isotope-labeled adenine into RNA for the study of conformational dynamics by NMR
Solution NMR spectroscopy is a well-established tool with unique advantages for structural studies of RNA molecules. However, for large RNA sequences, the NMR resonances often overlap severely. A reliable way to perform resonance assignment and allow further analysis despite spectral crowding is the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269771/ https://www.ncbi.nlm.nih.gov/pubmed/35802676 http://dx.doi.org/10.1371/journal.pone.0264662 |