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Effects of the combination of a monoclonal agonistic mouse anti-OX40 antibody and toll-like receptor agonists: Unmethylated CpG and LPS on an MB49 bladder cancer cell line in a mouse model

PURPOSE: The basis of the antitumor immunotherapy, of which the purpose is the stimulation of the immune system. We have used two of the Pathogen Associated Molecular Patterns: unmethylated CpG oligonucleotide, a ligand of Toll-like receptor 9 (TLR9), and lipopolysaccharide (LPS) which is recognized...

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Detalles Bibliográficos
Autores principales: Gulyás, Dominik, Kovács, Gábor, Jankovics, István, Mészáros, László, Lőrincz, Márta, Dénes, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269874/
https://www.ncbi.nlm.nih.gov/pubmed/35802726
http://dx.doi.org/10.1371/journal.pone.0270802