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Reward ameliorates depressive-like behaviors via inhibition of the substantia innominata to the lateral habenula projection

The lateral habenula (LHb) is implicated in emotional processing, especially depression. Recent studies indicate that the basal forebrain (BF) transmits reward or aversive signals to the LHb. However, the contribution of the BF-LHb circuit to the pathophysiology of depression still needs to be deter...

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Detalles Bibliográficos
Autores principales: Cui, Yuting, Huang, Xiaodan, Huang, Pengcheng, Huang, Lu, Feng, Zhao, Xiang, Xinkuan, Chen, Xinfeng, Li, Anan, Ren, Chaoran, Li, Haohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269896/
https://www.ncbi.nlm.nih.gov/pubmed/35857453
http://dx.doi.org/10.1126/sciadv.abn0193