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Increasing reproducibility, robustness, and generalizability of biomarker selection from meta-analysis using Bayesian methodology
A major limitation of gene expression biomarker studies is that they are not reproducible as they simply do not generalize to larger, real-world, heterogeneous populations. Frequentist multi-cohort gene expression meta-analysis has been frequently used as a solution to this problem to identify bioma...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269905/ https://www.ncbi.nlm.nih.gov/pubmed/35759523 http://dx.doi.org/10.1371/journal.pcbi.1010260 |