Calcitriol decreases HIV-1 transfer in vitro from monocyte-derived dendritic cells to CD4 + T cells, and downregulates the expression of DC-SIGN and SIGLEC-1

Dendritic cells (DCs) promote HIV-1 transmission by acting as Trojan horses, capturing viral particles, facilitating the infection of CD4+ T-cells. Vitamin D (VitD) has shown to decrease T cell activation, reducing susceptibility to HIV-1 infection of CD4+ T-cells in vitro; however, if VitD decrease...

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Detalles Bibliográficos
Autores principales: Alvarez, Natalia, Gonzalez, Sandra M., Hernandez, Juan C., Rugeles, Maria T., Aguilar-Jimenez, Wbeimar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269915/
https://www.ncbi.nlm.nih.gov/pubmed/35802715
http://dx.doi.org/10.1371/journal.pone.0269932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9269915/
https://www.ncbi.nlm.nih.gov/pubmed/35802715
http://dx.doi.org/10.1371/journal.pone.0269932

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